NECESSITY OF SURVEILLANCE RENAL BIOPSIES DURING INTRAVENOUS CYCLOPHOSPHAMIDE(IVCYC) THERAPY IN SYSTEMIC LUPUS ERYTHEMA TOSUS (SLE) NEPHRITIS.2173
نویسندگان
چکیده
منابع مشابه
Immunopathologic Studies of Systemic Lupus Erythema - tosus . II
The yG-globulin eluted at acid pH from kidney cortex homogenates and isolated glomeruli of five of six patients with lupus nephritis was found to exhibit antinuclear activity, which was not dependent on presence of fresh human serum. Specificity, as demonstrated by absorption of antinuclear activity, was related to nucleoprotein in three glomerular acid eluates and to DNA in two acid eluates as...
متن کاملPeripheral Blood Stem Cells of Patients with Systemic Lupus Erythema- tosus Show Altered Differentiation into Macrophages
Patients with systemic lupus erythematosus (SLE) often display clearance deficiencies for various targets like apoptotic cells. Most of the in vitro phagocytosis assays have been performed with leukocyte preparations from patients with SLE and may, therefore, be influenced by immunosuppressive drugs. We isolated circulating hematopoietic stem cells from patients with SLE to generate adherent ce...
متن کاملMorphological Patterns of Renal Disease in Systemic Lupus Erythematosus (SLE)
Aim: To observe the various morphological presentations of SLE on renal biopsy in terms of ISN / RPS classification. Settings and Design: Simple descriptive study, conducted in the Morbid Anatomy & Histopathology Department, University of Health Sciences, Lahore. Methods: We studied 30 biopsy samples of patients diagnosed as Systemic Lupus Erythematosus according to American Rheumatism Associat...
متن کاملAssociation of HLA-DRB1 Alleles in Juvenile-onset Systemic Lupus Erythematosus (SLE) in Iranian Children
Introduction Systemic Lupus Erythematosus (SLE) is a complex autoimmune and inflammatory disease. Many studies show HLA alleles can be associated with SLE. The aim of this study was to determine the association of HLA-DRB1 alleles with juvenile- onset in Iranian children. Materials and Methods At a case – control study, 31 children with systemic lupus erythematosus (case group) who referred to ...
متن کاملMonoclonal Antibodies for Systemic Lupus Erythematosus (SLE) †
A number of monoclonal antibodies (mAb) are now under investigation in clinical trials to assess their potential role in Systemic Lupus Erythematosus (SLE). The most frequently used mAb is rituximab, which is directed against CD20, a membrane protein expressed on B lymphocytes. Uncontrolled trials reported an improvement of SLE activity in non-renal patients and other studies even reported an i...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1996
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199604001-02197